Table 2.
Summary of the Down-Regulated Client Proteins of Hsp90 in MCF7 Cells with the Presence of SOMCL-16-175
| Uniprot | Protein | References |
|---|---|---|
| Q6PJG6 | BRAT1 (BRCA1 associated ATM activator 1) | Fierro-Monti et al., 2013 |
| P06493 | CDK1 (cyclin-dependent kinase 1) | Garcia-Morales et al., 2007 |
| P24941 | CDK2 (cyclin-dependent kinase 2) | Prince et al., 2005 |
| P26358 | DNMT1 (DNA (cytosine-5)-methyltransferase 1) | Zhou et al., 2008 |
| Q9Y6Y0 | IVNS1ABP (influenza virus NS1A-binding protein) | Zhang et al., 2011 |
| Q99538 | LGMN (protein encoded by the LGMN gene) | Lin et al., 2014 |
| Q02750 | MAP2K1 (dual specificity mitogen-activated protein kinase kinase 1) | Stancato et al., 1997 |
| P15941 | MUC1 (mucin 1) | Ren et al., 2006 |
| Q6P4R8 | NFRKB (nuclear factor related to kappa-B-binding protein) | Taipale et al., 2012 |
| P12004 | PCNA (proliferating cell nuclear antigen) | Wang et al., 2010 |
| Q96T88 | UHRF1 (ubiquitin like with PHD and ring finger domains 1) | Ding et al., 2016 |