Table 1. . Characteristics of 39 patients with cirrhosis caused by primary biliary cholangitis or primary sclerosing cholangitis.
| Characteristics | n = 39 (%) | |
|---|---|---|
| Diagnosis | – PBC | 13 (33) |
| – PSC | 26 (67) | |
| Gender | – Male | 17 (44) |
| – Female | 22 (56) | |
| Race | Caucasian | 39 (100) |
| Ascites | Present | 24 (62) |
| MELD-Na score | – 6–9 | 11 (28) |
| – 10–19 | 20 (51) | |
| – 20–40 | 8 (21) | |
| eGFR (ml/min/1.73 m2)† | – Stage 1 (≥90) | 12 (31) |
| – Stage 2 (≥60 and <90) | 14 (36) | |
| – Stage 3 (≥30 and <60) | 12 (31) | |
| – Stage 4 (≥15 and <30) | 1 (3) | |
| Survival outcomes | – Alive | 10 (26) |
| – Death | 11 (28) | |
| – Liver transplant | 18 (46) | |
| Hepatic malignancy | – Hepatocellular carcinoma | 4 (10) |
| – Cholangiocarcinoma | 3 (8) | |
| – Both | 3 (8) | |
| – None | 29 (74) | |
| Mean (SD) | ||
| Age (y) | 57.64 (11.85) | |
| MELD-Na score | 13.97 (6.82) | |
| Total bilirubin (mg/dl) | 3.46 (6.16) | |
| International normalized ratio | 1.36 (0.67) | |
| Serum Na (mmol/l) | 137.72 (3.94) | |
| Serum Cr (mg/dl) | 1.01 (0.39) | |
| Serum cystatin C (mg/l) | 1.13 (0.46) | |
| Plasma symmetric dimethylarginine (micromole/l) | 0.52 (0.31) |
†
Estimated using MDRD-4 equation [11].
eGFR: Estimated glomerular filtration rate; MDRD: Modification of diet in renal disease; MELD-Na: Model for end-stage liver disease-Na; PBC: Primary biliary cholangitis; PSC: Primary sclerosing cholangitis; SD: Standard deviation.