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. Author manuscript; available in PMC: 2020 Feb 4.
Published in final edited form as: Antiviral Res. 2018 Dec 3;162:61–70. doi: 10.1016/j.antiviral.2018.11.012

Figure 3: Histologic lesions in lungs after infection with mouse-adapted EV-D68.

Figure 3:

All mice were challenged with 10^6.5 CCID50 of the respective viruses in a 90 μl volume and sacrificed on day 2 post-infection for histopathology. Groups infected with the mouse passage 30 (MP30) and the MP30 plaque purified (MP30pp) viruses showed significant interstitial pneumonia severity scores compared to sham-infected mice. Each group consisted of 4 mice, except the sham-infected controls, which consisted of 3 mice. *P<0.05 by non-parametric test.