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. 2020 Feb 3;21:40. doi: 10.1186/s12931-020-1305-6

Table 3.

Separate effects and effect of the COPD and HB product term on chair rise and word memorization

Time to complete Chair-riseb Number of words memorizedb
M1 d M2e M1d M2e
COPDa 1 vs. 0 0.17 (0.07 to 0.27) 0.11 (0.01 to 0.2) −0.08 (− 0.18 to 0.02) −0.04 (− 0.14 to 0.06)
2 vs. 0 0.31 (0.22 to 0.40) 0.23 (0.14 to 0.32) −0.15 (− 0.24 to − 0.07) −0.09 (− 0.18 to − 0.003)
3 vs. 0 0.58 (0.43 to 0.73) 0.46 (0.31 to − 0.60) −0.19 (− 0.34 to − 0.03) −0.10 (− 0.26 to 0.05)
4 vs. 0 0.74 (0.46 to 1.01) 0.64 (0.37 to 0.91) −0.12 (− 0.4 to 0.16) −0.04 (− 0.32 to 0.24)
HB-(g/dl)c Association between lower HB level and time to complete chair rise 0.05 (0.03 to 0.06) 0.034 (0.02 to 0.05) −0.03 (− 0.04 to − 0.001) −0.02 (− 0.04 to − 0.001)
COPD + HB (g/dl) unit decrease in HB *COPD 1 vs. 0 0.1 (0.03 to 0.17) 0.1 (0.04 to 0.17) 0.11 (0.04 to 0.18) 0.11 (0.05 to 0.18)
Unit decrease in HB*COPD 2 vs. 0 0.04 (−0.02 to-0.11) 0.05 (−0.01 to 0.11) − 0.02 (− 0.08 to 0.04-) −0.03 (− 0.09 to 0.03)
Unit decrease in HB *COPD 3 vs. 0 0.08 (−0.01 to 0.18) 0.11 (0.02 to 0.2) −0.01(− 0.11 to 0.09)-) −0.02 (−  0.11 to 0.08)
Unit decrease in HB *COPD 4 vs. 0 0.36 (0.17 to 0.55) 0.36 (0.17 to 0.54) −0.03 (− 0.23 to 0.16) −0.04 (−  0.24 to 0.15)

aCOPD1 = mild; 2 = moderate; 3 = severe; 4 = very severe

bmodeled as the decrease per SD (SD− 1) in words memorized and time to complete chair raises

cHB was included as a continuous variable in g/dl

dadjustment model 1: sex and age, number of test repetitions; N = 8351 measurements; 5709 persons

emodel 2 additionally adjusts for blood pressure, myocardial infarction (MI), stroke, diabetes, total cholesterol, alcohol, depression grip strength and smoking, imputed from complete data for M1 and available values for M2

*Product term