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. 2020 Feb 3;20:92. doi: 10.1186/s12885-020-6587-z

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© The Author(s). 2020

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Survival curve analysis for sub-groups of CRC patients when defined by clinical presentation at surgery, comparing high and low expression levels of IL-36 s: by IL-36α production in patients with an invasion depth of T4 (a), lymph node metastasis (c), TNM III-IV (e), or right-sided colon CRC (g); or by IL-36γ production in patients with an invasion depth of T1–3 (b), no lymph node metastasis (d), TNM I-II (f), or left-sided colon CRC (h), using the Kaplan-Meier method and the log-rank test. X-axis represents days elapsed