Table 1.
Comparison of radiographic progression scoring methods in psoriatic arthritis trials
| Scoring method | Total joints, n (range of score) | Locations (total joints, n) | Damage score per joint | Additional features recorded | |
|---|---|---|---|---|---|
| Modified Steinbrocker [12, 13] | 42 (0–168) |
Hands (28) Wrists (2) Feet (12) |
0 = normal 1 = soft tissue swelling/osteopenia 2 = erosion 3 = erosion plus JSN 4 = total joint destruction |
– | |
| Typical modified Sharp used for PsA [4] | Erosion, 54; JSN, 50 (erosion, 0–270; JSN, 0–200; total, 0–470) |
Hands (28) Wrists (erosion, 14; JSN, 12) Feet (erosion, 12; JSN, 10) |
Erosion: 0 = no erosion 1 = 1 discrete erosion or < 21% of joint 2 = 2 erosions or 21–40% of joint 3 = 3 erosions or 41–60% of joint 4 = 4 erosions or 61–80% of joint 5 = extensive destruction, > 80% of joint |
JSN: 0 = normal joint 1 = asymmetrical/minimal narrowing 2 = definite narrowing with loss of ≤ 50% 3 = definite narrowing with loss of 51–99% 4 = absence of joint space, ankylosis |
Pencil in cup; joint space widening |
| Sharp-van der Heijde for PsA [4] | 52 (erosion, 0–320; JSN, 0–208; total, 0–528) |
Hands (28) Wrists (12) Feet (12) |
Erosion: 0 = no erosions 1 = discrete erosion 2 = large erosion not passing midline 3 = large erosion passing midline Scores can be combined if > 1 erosion per joint is present for a maximum score of 5 per joint in the hands and 10 per joint in the feet [Score of 5/10 if pencil-in-cup change or gross osteolysis present] |
JSN: 0 = normal joint 1 = asymmetrical/minimal narrowing up to 25% 2 = definite narrowing with loss ≤ 50% 3 = definite narrowing with loss of 51–99% or subluxation 4 = absence of joint space, ankylosis, or complete luxation [Score of 4 if pencil-in-cup change or gross osteolysis present] |
Pencil in cup; gross osteolysis |
| Psoriatic Arthritis Ratingen Score [14] | 40 (destruction, 0–200; proliferation, 0–160; total, 0–360) |
Hands (28) Wrists (2) Feet (10) |
Destruction: 0 = normal 1 = ≥ 1 erosion, > 1 mm interruption of cortical plate, with up to 10% destruction of joint surface 2 = 11–25% destruction of joint surface 3 = 26–50% destruction of joint surface 4 = 51–75% destruction of joint surface 5 = > 75% joint surface destruction |
Proliferation: 0 = normal 1 = bony proliferation of 1–2 mm or bone growth < 25% of original diameter 2 = bony proliferation 2–3 mm or bone growth of 25–50% 3 = bony proliferation > 3 mm or bone growth of > 50% 4 = bony ankylosis |
– |
JSN joint space narrowing, PsA psoriatic arthritis