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. 2020 Feb 4;20:56. doi: 10.1186/s12872-020-01365-9

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© The Author(s) 2020

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Transmission electron microscopy assessment for modulating autophagy. (A) Transmission electron microscopy indicated significant changes of autophagosomes in the four different groups. (B) Transmission electron microscopy showed that there was a significant increase of autophagosomes in the DCM group compared with the control group. Quantitative assessment demonstrated that autophagosomes were significantly increased in the rapamycin group, and they were decreased in the 3-MA group compared with the DCM group. ^†††P < 0.001 vs Control, ^***P < 0.01 and ^#P < 0.05 vs DCM. The arrows indicated the double membrane autophagosomes in the different groups