Table 4.
Total | ISS < 16 | ISS ≧ 16 | |||||||
---|---|---|---|---|---|---|---|---|---|
Adjusted HR | 95% CI | 95% CI | Adjusted HR | 95% CI | 95% CI | Adjusted HR | 95% CI | 95% CI | |
Either modafinil or methylphenidate (N = 1690) | 0.82 *** | 0.70 | 0.83 | 0.78 *** | 0.68 | 0.80 | 0.89 | 0.74 | 1.02 |
PDC 1—50% (N = 1264) | 0.87 ** | 0.71 | 0.88 | 0.82 *** | 0.69 | 0.86 | 0.95 | 0.76 | 1.09 |
PDC 51—100% (N = 426) | 0.78 *** | 0.69 | 0.79 | 0.73 *** | 0.67 | 0.76 | 0.85 * | 0.73 | 0.97 |
Modafinil (N = 933) | 0.83 *** | 0.71 | 0.84 | 0.78 *** | 0.69 | 0.82 | 0.90 | 0.76 | 1.05 |
PDC 1—50% (N = 685) | 0.89 ** | 0.73 | 0.90 | 0.84 *** | 0.71 | 0.87 | 0.97 | 0.78 | 1.11 |
PDC 51—100% (N = 248) | 0.78 ** | 0.70 | 0.79 | 0.73 *** | 0.68 | 0.77 | 0.85 | 0.73 | 1.01 |
Methylphenidate (N = 893) | 0.82 *** | 0.69 | 0.92 | 0.77 *** | 0.67 | 0.79 | 0.89 | 0.73 | 1.01 |
PDC 1—50% (N = 680) | 0.85 *** | 0.70 | 0.87 | 0.80 *** | 0.68 | 0.85 | 0.93 | 0.73 | 1.08 |
PDC 51—100% (N = 213) | 0.78 *** | 0.69 | 0.80 | 0.73 *** | 0.67 | 0.76 | 0.85 * | 0.72 | 0.96 |
Modafinil only (N = 797) | 0.88 * | 0.82 | 0.96 | 0.94 * | 0.79 | 0.93 | 0.96 | 0.86 | 1.17 |
PDC 1—50% (N = 584) | 0.90 | 0.82 | 1.02 | 0.85 * | 0.80 | 0.99 | 1.00 | 0.86 | 1.24 |
PDC 51—100% (N = 213) | 0.85 * | 0.81 | 0.93 | 0.80 ** | 0.78 | 0.90 | 0.93 * | 0.85 | 0.99 |
Methylphenidate only (N = 757) | 0.84 * | 0.78 | 0.90 | 0.77 *** | 0.76 | 0.88 | 0.92 | 0.82 | 1.12 |
PDC 1—50% (N = 579) | 0.86 * | 0.79 | 0.93 | 0.81 *** | 0.76 | 0.89 | 0.94 | 0.83 | 1.14 |
PDC 50—100% (N = 178) | 0.83 ** | 0.77 | 0.89 | 0.78 *** | 0.74 | 0.86 | 0.90 * | 0.81 | 0.96 |
Modafinil & Methylphenidate (N = 136) | 0.79 *** | 0.64 | 0.85 | 0.74 *** | 0.62 | 0.83 | 0.86 | 0.67 | 1.05 |
PDC 1—50% (N = 101) | 0.81 *** | 0.65 | 0.86 | 0.77 *** | 0.63 | 0.84 | 0.88 | 0.69 | 1.06 |
PDC 50—100% (N = 35) | 0.78 *** | 0.63 | 0.79 | 0.70 *** | 0.61 | 0.74 | 0.81 * | 0.66 | 0.94 |
HR hazard ratio, CI confidence interval, Adjusted HR Adjusted variables listed in Table 1
* P < 0.05, ** P < 0.01, *** P < 0.001