Table 3.

Physical health characteristics of 1049 SHIP participants with schizophrenia or schizo-affective disorder who reported using any antipsychotic medication in the past 4weeks, by use of clozapine

	Clozapine
	No		Yes
	n	%	n	%	Adjusted OR†	CI
Diabetes	145	18.6	73	28.9	1.744***	1.249–2.435
Epilepsy	50	6.3	28	11.0	1.656*	1.006–2.725
Heart attack	18	2.3	5	2.0	0.795	0.284–2.229
Respiratory problems	134	17.0	56	22.0	1.312	0.916–1.881
Head injury	166	21.0	51	20.0	0.898	0.627–1.288
Chronic pain	230	29.1	57	22.4	0.685*	0.488–0.963
Sleep apnoea	319	42.9	103	43.5	1.080	0.800–1.460
Metabolic syndrome	318	55.5	153	73.6	2.300***	1.610–3.284
HDL§	330	57.9	136	67.0	1.397	0.985–1.981
Triglycerides§	304	53.1	137	66.5	1.575**	1.115–2.226
Glucose§	175	30.9	90	46.2	1.9323***	1.358–2.723
Blood pressure§	368	48.0	143	56.7	1.469**	1.096–1.967
Waist circumference§	619	81.0	225	89.3	2.004**	1.285–3.126
BMI
Underweight/normal	187	24.3	41	16.3	1.0
Overweight	228	29.6	65	25.9	1.354	0.870–2.108
Obese	356	46.2	145	57.8	1.899***	1.279–2.725
IPAQ
Low	379	48.5	129	51.0	1.089	0.682–1.739
Moderate	302	38.6	95	37.5	1.052	0.650–1.703
High	101	12.9	29	11.5	1.0
Self assessment of doing enough physical activity	275	35.0	96	37.8	1.066	0.790–1.437

SHIP, survey of high impact psychosis; OR, odds ratio; CI, confidence interval; IPAQ, International physical activity questionnaire, divided into low, moderate and high amounts of physical activity.

Missing cases: diabetes = 16; epilepsy, heart attack, respiratory problems, head injury, chronic pain = 4; sleep apnoea = 69; metabolic syndrome = 268; HDL = 6; triglycerides = 1; glucose = 1; blood pressure = 30; waist circumference = 3; BMI = 27; IPAQ = 14.

^†All variables are adjusted for chronicity and diagnosis.

^§Elevated based on International Diabetes Federation criteria.

* p < 0.05, ** p < 0.01, and *** p < 0.001.