Table 6.
Rates of Polypharmacy among 1049 SHIP participants with schizophrenia or schizo-affective disorder who reported using any antipsychotic medication in the past 4 weeks, by use of clozapine
| Clozapine | ||||||
|---|---|---|---|---|---|---|
| No | Yes | |||||
| n | % | n | % | Adjusted OR† | 95% CI | |
| Antipsychotics | ||||||
| One | 557 | 70.3 | 178 | 69.3 | 1.0 | |
| More than one | 235 | 29.6 | 79 | 30.7 | 0.934 | 0.713–1.332 |
| Antidepressants | ||||||
| None | 540 | 68.2 | 168 | 65.4 | 1.0 | |
| Any | 252 | 31.8 | 89 | 34.6 | 1.166 | 0.860–1.580 |
| Mood stabilisers | ||||||
| None | 631 | 79.7 | 192 | 74.7 | 1.0 | |
| Any | 161 | 20.3 | 65 | 25.3 | 1.433* | 1.010–2.033 |
| Anxiolytics/hypnotics | ||||||
| None | 655 | 82.7 | 217 | 84.4 | 1.0 | |
| Any | 137 | 17.2 | 40 | 15.6 | 0.880 | 0.595–1.303 |
SHIP, survey of high impact psychosis; OR, odds ratio; CI, confidence interval.
†
All variables are adjusted for chronicity and diagnosis.
*p < 0.05, **p < 0.01, and ***p < 0.001.