Table 4.
Univariate analysis of early risk factors for psychosis in the cohorts presented in HR
| NFBC 1966 N = 11 621 |
NFBC 1986 N = 9321 |
|||
|---|---|---|---|---|
| Predictor | n/N (%) | HR (95%CI) | n/N (%) | HR (95%CI) |
| Sex | ||||
| Male | 68/118 (57.6%) | 1.30 (0.90–1.87) | 96/177 (54.2%) | 1.12 (0.84–1.51) |
| Female | 50/118 (42.4%) | 1 | 81/177 (45.8%) | 1 |
| Parental psychosis (until age 27) | ||||
| No | 98/118 (83.1%) | 1 | 155/177 (87.6%) | 1 |
| Yes | 20/118 (16.9%) | 3.01 (1.86–4.88) | 22/177 (12.4%) | 2.99 (1.91–4.67) |
| Mother's education at birth | ||||
| Basic education | 80/117 (68.4%) | 0.77 (0.51–1.17) | 41/143 (28.7%) | 1.15 (0.79–1.66) |
| Secondary education | 32/117 (27.4%) | 1 | 91/143 (63.6%) | 1 |
| Higher education | 5/117 (4.3%) | 0.87 (0.34–2.23) | 11/143 (7.7%) | 1.29 (0.69–2.41) |
| Place of residence | ||||
| Urban | 38/118 (32.2%) | 1 | 82/171 (48.0%) | 1 |
| Rural | 80/118 (67.8%) | 1.08 (0.74–1.59) | 89/171 (52.0%) | 1.21 (0.90–1.64) |
| Maternal age | ||||
| <20 | 10/117 (8.5%) | 0.89 (0.46–1.72) | 9/177 (5.1%) | 1.23 (0.63–2.41) |
| 20–35 | 83/117 (70.9%) | 1 | 143/177 (80.8%) | 1 |
| >35 | 24/117 (20.5%) | 1.26 (0.80–1.98) | 25/177 (14.1%) | 1.01 (0.72–1.68) |
| Paternal age | ||||
| <25 | 19/112 (17.0%) | 0.69 (0.42–1.14) | 28/176 (15.9%) | 0.94 (0.62–1.41) |
| 25–40 | 81/112 (72.3%) | 1 | 134/176 (76.1%) | 1 |
| >40 | 12/113 (10.7%) | 0.80 (0.44–1.47) | 14/176 (8.0%) | 1.21 (0.70–2.10) |
HR, hazard ratio; 95% CI, 95% confidence interval.