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. 2020 Feb 3;19:13. doi: 10.1186/s12940-020-0566-3

Table 3.

Associations of noise exposure, genetic models and lifestyles with risk of NIHL

Unadjusted OR (95%CI) Unadjusted P Adjusted OR (95% CI) Adjusted P
Kurtosis Complex noise/Steady noise 1.753 (1.209–2.540) 0.003 1.806 (1.235–2.643) 0.002
CNEa ≥85/<85 0.845 (0.478–1.494) 0.562 0.808 (0.454–1.437) 0.468
rs12195525
 Additive GT/GG 0.628 (0.395–0.996) 0.048 0.618 (0.388–0.985) 0.043
TT/GG 0.777 (0.234–2.578) 0.680 0.655 (0.192–2.227) 0.498
 Dominant TT + GT/GG 0.643 (0.415–0.997) 0.048 0.622 (0.400–0.969) 0.036
 Recessive TT/GG + GT 0.831 (0.251–2.751) 0.761 0.700 (0.206–2.378) 0.568
 Allele T/G 0.708 (0.476–1.054) 0.089 0.686 (0.460–1.025) 0.066
 Smoking Yes/No 1.388 (1.010–1.907) 0.043 1.486 (1.021–2.161) 0.038
 Drinking Yes/No 1.269 (0.894–1.802) 0.182 1.273 (0.869–1.865) 0.215
 Sleeping time 21:00~23:00/~ 21:00 1.009 (0.498–2.046) 0.980 1.017 (0.495–2.090) 0.963
23:00~/~ 21:00 0.709 (0.328–1.535) 0.383 0.760 (0.344–1.676) 0.496
 Sleeping duration ≥8 h/<8 h 1.043 (0.752–1.445) 0.803 1.150 (0.818–1.615) 0.422
 Video volume High/Low 1.681 (1.156–2.444) 0.007 1.611 (1.101–2.358) 0.014
 Fruits/vegetables Inadequate/Adequate 1.198 (0.852–1.685) 0.298 1.283 (0.906–1.818) 0.161
 Physical exercise Regular/Never 0.636 (0.452–0.896) 0.010 0.598 (0.419–0.852) 0.004
 Life pressure High/Low 1.316 (0.903–1.916) 0.153 1.253 (0.855–1.836) 0.248
 Working pressure High/Low 1.387 (0.919–2.092) 0.119 1.341 (0.883–2.036) 0.169
 HPDs No/Yes 1.316 (0.958–1.807) 0.090 1.330 (0.959–1.846) 0.087

Adjusted for gender, age, education and working years.

aAdjusted for gender, age and education.

P value <0.05 was considered statistically significant and maintains significance using the Benjamini-Hochberg procedure with the false discovery rate at 0.15