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. 2008 Jan 23;2008(1):CD004057. doi: 10.1002/14651858.CD004057.pub3

Hazard 2000.

Methods RCT
Participants N=489; Mean age (yrs): 37.7; Gender (female): 40%; Diagnosis: reported LBP within 11 days after an occupational injury, unclear whether sciatica was included. 
 Setting: occupational
Interventions (E1) 'Back Home' booklet with biopsychosocial information and usual care (N=63); 
 (E2) 'Back Home' booklet with biopsychosocial information plus advice to perform exercises and usual care (N=56); 
 (E3) Advice to perform exercises and usual care (N=61); 
 (C) Usual care: no booklet nor exercises (N=59).
Outcomes Back pain specific functional status: 
 Pain/function score (0 to 100), mean change and 95% CI at 1 and 3 wk: 
 (E1) vs. (C) ‐8.7 (‐17.4 to ‐0.03), # ‐6.3 (‐14.6 to 2.0) 
 (E2) vs. (C) ‐0.1 (‐9.0 to 8.9), ‐4.0 (‐12.6 to 4.6) 
 (E3) vs. (C) ‐7.9 (‐16.7 to 0.8), # ‐1.4 (‐9.9 to 7.1)
Aberdeen Pain & Function scale (0 to 100), mean change and 95% CI at 1 wk: 
 (E1) vs. (C) ‐3.8 (‐7.7 to 0.1) # 
 (E2) vs. (C) ‐1.9 (‐5.8 to 2.1) 
 (E3) vs. (C) ‐5.3 (‐9.3 to ‐1.4) #
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation? Unclear risk Unclear from text.
Allocation concealment? Low risk A ‐ Adequate
Blinding? 
 All outcomes ‐ patients? Unclear risk Unclear from text.
Blinding? 
 All outcomes ‐ providers? Low risk  
Blinding? 
 All outcomes ‐ outcome assessors? Low risk  
Incomplete outcome data addressed? 
 All outcomes ‐ drop‐outs during intervention? Low risk  
Incomplete outcome data addressed? 
 All outcomes ‐ drop‐outs during follow‐up? Low risk  
Incomplete outcome data addressed? 
 All outcomes ‐ ITT analysis? High risk  
Similarity at baseline characteristics? Low risk  
Co‐interventions avoided or similar? High risk  
Compliance acceptable? Unclear risk Unclear from text.