Figure 2.

Different approaches for error correction. (A) Enzymatic error correction uses either mismatch binding proteins with filtration to remove DNA with errors, or enzymes that cleave erroneous DNA. (B) DNA that has been sequenced can be located and physically removed by micropipettes 31, or lasers 32. (C) Next generation sequencing of barcoded molecules can identify correct molecules that are then amplified with the barcode as a primer 33. (D) Comparison of the different error correction methods.