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. 2003 Jan 20;2003(1):CD003383. doi: 10.1002/14651858.CD003383

Connor 2002.

Methods Randomised, placebo‐controlled double‐blind; 2 parallel groups
Participants Outpatients with generalized anxiety disorder (DSM‐IV) ; HAMA total score 16 or above (per‐protocol; n=35); University outpatient setting, US
Interventions 140 mg kavalactones daily for 1 week, then 280 mg kavalactones daily for 3 weeks
Outcomes HAM‐A total score. Mean difference, 95% confidence interval ‐2.8; ‐5.4 to ‐0.2
Notes 'No evidence of withdrawal or sexual side effects' 
 Jadad score: 5
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear