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. 2003 Jan 20;2003(1):CD002886. doi: 10.1002/14651858.CD002886

Storr 1987.

Methods setting: children's hospital, Brighton, England 
 design: randomised double‐blind controlled trial, parallel design 
 length of intervention: 36 hours 
 masking: double‐blind 
 excluded: stated 
 withdrawals: stated 
 baseline characteristics: similar in both treatment groups
Participants 140 children 
 mean age: 5.3 y: M 97, F 43 
 prednisone arm: n=67 
 control arm: n=73 
 inclusion criteria: children hospitalised with moderate or severe asthma 
 exclusion criteria: Other lung illnesses such as croup, pneumonia, pertussis. 
 Vomited drink or previous "steroids" in the most recent 48h
Interventions Oral prednisolone3mg/kg prednisolone in water (one dose) 
 (children<5y got 30mg and others got 60mg) 
 OR 
 grapefruit juice
all children got standard therapy of nebulised salbutamol 5mg in 2 ml saline on admission and >3 times daily as needed
Outcomes Discharge at first re‐examination (4h)
% expected PEFR (6h)
Requirement for suplimentary therapy
Notes Jadad score 5
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Low risk A ‐ Adequate