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. 2003 Jan 20;2003(1):CD002886. doi: 10.1002/14651858.CD002886

Ho 1994.

Methods setting: Paediatric emergency department, Perth, Australia 
 design: randomised, double‐blind controlled trial, parallel design 
 length of intervention: length of hospitalisation up to 5 days 
 masking: double blind 
 excluded: stated 
 withdrawals: stated 
 baseline characteristics: similar in both treatment groups
Participants 58 children 
 mean age: 4 y: M 24, F 34 
 prednisolone arm: n=31 
 control arm: n=27 
 inclusion criteria: children age 2 ‐ 14 attending hospital emergency department with acute asthma with saturation <= 93% and requiring admission 
 exclusion criteria: Seriously ill with asthma, previous steroids used (any oral or inhaled steroids >400 mcg/d) 
 Child < 2yrs excluded
Interventions 1mg/kg oral prednisolone given at admission 
 OR 
 placebo
all children got standard therapy of regular beta 2 agonists. Some received theophylline and ipratropium bromide
Outcomes Length of stay
Change in SaO2 (12, 24 hrs)
Change in predicted FEV1 (12, 24, 36hrs)
Change in predicted PEFR (12, 24, 36 hrs)
Notes Jadad score 4
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear