Table 1. Susceptibility of different organisms to quinazoline derivatives.

	MIC in μg/mLa
Microorganisms	11626252	11626141	11626142	RIF
Bacillus subtilis	≥100	≥100	≥100	0.3
Candida albicans	≥100	≥100	44.3	2.2
Corynebacterium diphtheriae	≥100	≥100	44.3	0.5
Corynebacterium glutamicum ATCC13032	47.2	66.8	75	0.004
Enterococcus faecalis	≥100	≥100	≥100	3.9
Escherichia coli PQ37	≥100	≥100	≥100	6.5
Listeria monocytogenes	≥100	≥100	≥100	0.6
Micrococcus luteus	≥100	≥100	≥100	0.2
Mycobacteroides abscessus subsp. abscessus 2005–0524	≥100	62.4	100	18.1
Mycobacterium avium ATCC15769	≥100	≥100	49.1	27.3
Mycobacteroides abscessus subsp. bolletii 1999–0888	≥100	≥100	≥100	24.8
Mycobacterium bovis BCG Pasteur	1.6	0.9	0.8	0.0008
Mycobacterium canettii STB-L	0.03	0.05	0.2	0.001
Mycobacterium marinum Strain M	0.007	0.1	0.8	0.2
Mycobacteroides abscessus subsp. massiliense 2005–0484	≥100	≥100	≥100	9.5
Mycobacterium smegmatis mc2155	32.3	38.4	75.6	0.9
Mycobacterium tuberculosis Erdman	0.02	0.01	0.1	0.001
Mycobacterium tuberculosis H37Rv	0.02	0.04	0.09	0.0008
Mycobacterium tuberculosis HN878	0.03	0.05	0.2	0.0006
Mycobacterium tuberculosis MDR 59744	0.02	0.02	0.09	≥10
Mycolicibacterium vaccae ATCC 15483	≥100	≥100	≥100	6.6
Pseudomonas aeruginosa	≥100	≥100	≥100	0.2
Pseudomonas putida	≥100	≥100	≥100	3
Salmonella typhimurium	≥100	≥100	≥100	0.8
Staphylococcus aureus	≥100	≥100	≥100	1.4

^a Values in bold are ≤ 10 μg/mL