Fig. 3.

Using the results from glycan-array analyses to interpret experimental data. A lectin (or a glycan-binding antibody) can be applied to glycan arrays and experimental samples in separate experiments. Analysis software is applied to the glycan-array data to determine the lectin specificities, and the amount of lectin binding to the sample with unknown glycans is quantified. The output from the glycan-array analysis is combined with the data from the sample to produce an estimation of the glycans that are present in the sample. This scheme also could be used with integrated data from multiple lectins, and with data acquired after treatments with glycosidases.