Figure 1.

Cortisol levels in amniotic fluid of conceptuses. In accordance with physiological observations in humans [31], AF cortisol levels increased from mid (78 gd) to later gestation (110 gd) in both control and ZIKV-affected litters. Numbers below X-axis represent average cortisol level in maternal plasma and the number of tested gilts (n). Fetal cortisol data from both control gilts on middle and right panels were combined because both gilts were sampled at 110 gd. Cortisol levels in fetuses were compared using two-sided Mann-Whitney U test (p-value). The line represents mean value. * – at 78 gd, maternal cortisol was measured only in one control gilt.