Figure 3.
Evolution of vegetation infection after challenge with parent L. lactis pIL253 and recombinant L. lactis Coa or L. lactis vWbp (a) and in vitro killing by platelets (b). (a) Groups of 6–10 rats were inoculated with of 107 CFU and sacrificed at various times after challenge. Data represent mean ± SD of vegetation bacterial titres. *, P < 0.01 vs L. lactis pIL253 and L. lactis vWbp; # P < 0.01 vs L. lactis pIL253, as compared by the one-way ANOVA followed by Tukey’s multiple comparisons test. (b) Killing of L. lactis by platelets after 4 and 24 h of exposure. *, P < 0.05 by one-way ANOVA followed by Tukey’s multiple comparisons test.