Table 2.

Cardiac Function of WT and TRIM72 C144S mice.

	WT	TRIM72 C144S
Heart rate	493.8±20.0	520.8±9.3
Volume; s	32.6±1.7	25.5±1.4*
Volume; d	78.3±2.8	64.9±2.9*
EF	58.3±0.9	60.7±0.8
%FS	30.5±0.6	32.1±0.5
Diameter; s	2.9±0.1	2.6±0.1*
Diameter; d	4.2±0.1	3.9±0.1*
LVAW; d	0.7±0.01	0.7±0.01
LVAW; s	1.1±0.02	1.1±0.01
LVPW; d	0.7±0.01	0.7±0.01
LVPW; s	1.1±0.01	1.1±0.02
LV mass	79.7±3.0	75.0±0.2
LVOT mean gradient	2.6±0.2	2.4±0.1
LVOT mean velocity	811.2±23.0	773.6±20.9
mmHg peak gradient	6.3±0.3	6.0±0.2
mm/s Peak Velocity	1255.0±27.9	1223.6±21.6
PA mean gradient	0.7±0.1	0.8±0.1
PA mean velocity	430.2±14.7	442.8±22.2
PA peak gradient	2.1±0.1	2.5±0.2
PA peak Velocity	731.2±15.7	784.6±37.3

Echocardiography was performed in WT and TRIM72 C144S male mice. Values are mean ± SEM (WT n=5; TRIM72 C144S n=5); T-test and Mann-Whitney test were performed to assess significance

^*p<0.05 vs WT