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. 2019 Sep 11;22(2):353–361. doi: 10.1038/s41436-019-0649-0

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© American College of Medical Genetics and Genomics 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Responses given by participants who viewed reports with positive test results to the question “If John and Jane have a child, will the child have cystic fibrosis?” When asked to produce the numeric probability that the first child would have cystic fibrosis (Table 2, Section 4), participants who felt it was “likely” that the first child would have cystic fibrosis had mean estimates of 34% (SD = 21%) if they had seen the standard report, compared with 31% (SD = 12%) if they had seen the user-centered report (no significant difference, U = 473, p = 0.7). Participants who felt it was “unlikely” that the first child would have cystic fibrosis had mean estimates of 25% (SD = 0.4%) if they had seen the standard report, compared to 27% (SD = 14%) if they had seen the user-centered report (no significant difference, U = 100, p = 0.4).