Table 4.
Power comparison between Bayesian method and theZ-test method
FFa | Method | 0.1× | 0.2× | 0.5× | 1× | 2× | 5× |
---|---|---|---|---|---|---|---|
0.04 | BF | 0.8306 | 0.9845 | 0.9998 | 1.0000 | 1.0000 | 1.0000 |
0.04 | Z | 0.8125 | 0.9779 | 0.9993 | 1.0000 | 1.0000 | 1.0000 |
0.06 | BF | 0.9963 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 |
0.06 | Z | 0.9930 | 0.9999 | 1.0000 | 1.0000 | 1.0000 | 1.0000 |
0.08 | BF | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 |
0.08 | Z | 0.9999 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 |
0.12 | BF | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 |
0.12 | Z | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 |
FFb | Method | 0.1× | 0.2× | 0.5× | 1× | 2× | 5× |
---|---|---|---|---|---|---|---|
0.04 | BF | 0.0602 | 0.0800 | 0.3620 | 0.6710 | 0.8830 | 0.9914 |
0.04 | Z | 0.0396 | 0.0529 | 0.3500 | 0.6550 | 0.8436 | 0.9832 |
0.06 | BF | 0.1797 | 0.2365 | 0.7398 | 0.9575 | 0.9973 | 1.0000 |
0.06 | Z | 0.1521 | 0.2240 | 0.7039 | 0.9321 | 0.9932 | 1.0000 |
0.08 | BF | 0.3622 | 0.4539 | 0.9391 | 0.9981 | 1.0000 | 1.0000 |
0.08 | Z | 0.3540 | 0.4535 | 0.9163 | 0.9952 | 0.9999 | 1.0000 |
0.12 | BF | 0.7092 | 0.8348 | 0.9994 | 1.0000 | 1.0000 | 1.0000 |
0.12 | Z | 0.6767 | 0.7973 | 0.9984 | 1.0000 | 1.0000 | 1.0000 |
The comparisons were done at different FFs (row) and different coverages (column). The recorded power is at the type I error of 0.001.
BF Bayesian method,Z Z-test.
aSimulated based on empirical data of chromosomes 13, 18, and 21.
bBased on three 5-Mb regions each drawn from the three chromosomes.