Table. 1.
Correlation between MELK expression and clinicopathological parameters in 250 patients with endometrial cancer.
| Expression of MELK | ||||
| Total | Low (%) | High (%) | P value | |
| Age | ||||
| < 45 years old | 25 | 9 (36.0) | 16 (64.0) | 0.293 |
| ≥45 years old | 225 | 109 (48.4) | 116 (51.6) | |
| Menopause | ||||
| Yes | 163 | 82 (50.3) | 81 (49.7) | 0.186 |
| No | 87 | 36 (41.4) | 51 (58.6) | |
| Pregnancy | ||||
| Yes | 239 | 113 (47.3) | 126 (52.7) | 1 |
| No | 11 | 5 (45.5) | 6 (54.5) | |
| Family history | ||||
| Yes | 15 | 6 (40.0) | 9(60.0) | 0.605 |
| No | 235 | 112(47.7) | 123 (52.3) | |
| Pathological type | ||||
| Ademocarcinoma | 229 | 108(47.2) | 121 (52.8) | 1 |
| Non-ademocarcainoma | 21 | 10(38.5) | 11 (61.5) | |
| Clinical Stage (FIGO) | ||||
| Ⅰ | 174 | 93 (53.4) | 81 (46.6) | 0.001* |
| Ⅱ | 32 | 15 (46.9) | 17 (53.1) | |
| Ⅲ-Ⅳ | 44 | 10 (22.7) | 34 (77.3) | |
| Grade | ||||
| 1 | 123 | 77 (62.6) | 46 (37.4) | 0.000* |
| 2 | 85 | 28 (32.9) | 57 (67.1) | |
| 3 | 42 | 13 (31.0) | 29 (69.0) | |
| LN metastasis | ||||
| Yes | 24 | 6 (25.0) | 18 (75.0) | 0.03* |
| No | 226 | 113 (50.0) | 113 (50.0) | |
FIGO, International Federation of Gynecology and Obstetrics; LN, Lymph node.
⁎
P < 0.05, Statistically significant.