Table 3.

Correlation and association of SNRNP200, SRRM1 and SRSF3 expression levels with clinical features of prostate cancer aggressiveness. Data of correlations represent the coefficient "r". Data of associations represent the difference between means of each group ± standard deviation. Significant prostate cancer (SigPCa) is defined as Gleason score ≥ 7. Asterisks (* p < 0.05; ** p < 0.01; ** p < 0.001) indicate statistically significant differences between groups.

	Correlations		Associations
	Gleason score	T- Stage	Perineural Invasion	Lymphovascular Invasion	SigPca
RNU4	0.122	0.239*	9,664,718,823 ± 3,162,530,673 **	7,730,140,948 ± 3,078,119,236 *	7,526,218,231 ± 3,298,861,131 *
RNU6	0.235*	0.075	230,034,826 ± 72,616,606 **	119,362,920 ± 102,513,311	163,738,961 ± 75,084,561 *
PRPF40A	0.184	0.214	1,801,231 ± 878,336 *	1,669,010 ± 855,998	1,789,300 ± 832,618 *
SF3B1	0.312**	0.121	9,003,875 ± 3,487,752 *	10,853,954 ± 4,783,529 **	5,808,930 ± 3,941,225
U2AF2	0.09	0.083	714,287 ± 348,778 *	807,889 ± 481,128	347,329 ± 370,880
SNRNP200	0.264*	0.247*	2,681,185,105 ± 1,175,955,224 *	2,812,777,484 ± 1,275,566,115 *	2,125,357,393 ± 1,042,911,480 *
RNU12	0.321**	0.178	395,441 ± 132,486 **	133,816 ± 149,579	208,236 ± 139,628
ESRP1	0.319**	0.166	1,658,118 ± 916,550	2,151,271 ± 1,084,569	1,874,015 ± 936,328 *
ESRP2	0.281*	0.254*	1,953,298 ± 1,179,570	3,964,985 ± 1,266,549 **	2,941,102 ± 1,300,974 *
KHDRBS1	0.128	0.215	8,816,079 ± 4,355,945 *	7,047,264 ± 5,942,380	10,326,770 ± 4,988,242 *
MAGOH	0.331**	0.173	572,836 ± 376,052	1,036,475 ± 489,737 *	772,768 ± 395,132
NOVA1	0.131	0.211	1,375,554 ± 1,240,422	2,891,594 ± 1,397,232 *	1,968,158 ± 1,417,671
PTB	0.189	0.197	462,842 ± 504,081	707,443 ± 685,520	923,496 ± 547,502
RBM3	0.141	0.139	1,831,860 ± 1,133,513	2,948,642 ± 1,333,148 *	2,051,801 ± 1,189,264
RBM45	0.145	0.159	2,144,099 ± 1,086,705	2,444,946 ± 1,430,495	1,613,514 ± 1,237,865
SND1	0.236*	0.167	6,829,797 ± 3,127,408 *	8,116,316 ± 3,698,131 *	7,483,290 ± 3,461,207 *
SRSF2	0.284*	0.161	903,780 ± 409,990 *	1,099,682 ± 533,886 *	914,182 ± 460,892
SRSF3	0.289*	0.274*	13,698,858 ± 5,050,576 **	12,653,631 ± 5,712,504 *	10,070,038 ± 5,031,330 *
SRSF4	0.139	0.169	2,131,612 ± 857,251 *	3,422,072 ± 1,068,338 **	941,268 ± 902,489
SRSF5	0.055	0.129	105,348,741 ± 37,924,790 **	141,185,003 ± 48,026,387 **	35,477,260 ± 37,643,655
SRSF9	0.088	0.211	33,397,890 ± 12,917,648 *	28,501,453 ± 15,538,733	26,539,564 ± 14,468,693
SRSF10	0.057	0.218	10,135,257 ± 4,077,596 *	10,622,878 ± 5,604,567	4,248,356 ± 4,293,783
SRRM1	0.211*	0.224*	9,522,292 ± 4,314,271 *	9,444,197 ± 4,007,860 *	9,478,531 ± 4,760,093 *
SRRM4	−0.154	0.107	53,981 ± 33,971	-2375 ± 34,689	47,458 ± 36,610
TIA1	0.114	0.246*	5,965,156 ± 2,459,924 *	6,334,929 ± 2,989,097	5,493,989 ± 2,630,409*
TRA2A	0.141	0.191	27,361,791 ± 12,693,441 *	39,100,412 ± 15,368,002	29,010,940 ± 15,801,444