TABLE 3.
Probiotic related genes present in Lactobacillus plantarum strains DHCU70 and DKP1.
| Gene | Putative function | Response |
Lactobacillus plantarum strains |
|
| DHCU70 | DKP1 | |||
| Stress resistance genes | ||||
| dltD (L. rhamnosus) | d- anylation of LTA | Acid and defensin Resistance | + | + |
| dltA (L. reuteri) | d- anylation of LTA | Acid and defensin Resistance | + | + |
| DNA and protein protection and repair | ||||
| dps(L. reuteri) | DNA protection during starvation | DNA protection during starvation | + | + |
| clpL(L. reuteri) | clpATPase (chaperon) | Acid and bile tolerance | + | + |
| clpC (L. plantarum) | Persistence capacity in vivo | + | + | |
| msrB (L. reuteri) | Methionine sulfoxide reductase | Persistence capacity in vivo | + | + |
| luxS (L. reuteri) | Activated methyl cycle | Persistence capacity in vivo | + | + |
| Active removal of stressors | ||||
| gadB (L. acidophilus) | GABA transporter | Acid tolerance | + | + |
| bsh (L. plantarum) | Bile salt hydrolase | Bile salt resistance | + | + |
| Anti-pathogenic effect | ||||
| luxS (L. reuteri) | Production of AI-2. AI-3 | Autoinduction ability | + | + |
| Immunomodulation | ||||
| dltB (L. plantarum) | d- anylation of LTA | Anti-inflammatory potential in vitro in PBMCs and in vivo in a murine model of colitis or in a rat model for visceral pain perception | + | + |
| dltD (L. reuteri) | d- anylation of LTA | Resistance to human β-defensin-2 | + | + |
| Adhesion ability | ||||
| Mucin22 | Mucin binding | Adhesion ability | + | + |
| fbp | Fibronectin binding | Adhesion ability | + | + |