. 2020 Jan 29;11:54. doi: 10.3389/fmicb.2020.00054

TABLE 3.

Median MIC (range) in cation supplemented and/or pH adjusted CAMHB and artificial urine.

	MIC [mg/L]
	CAMHB pH 7.3			CAMHB pH 6.1			Artificial urine pH 6.1		Artificial urine pH 7.3

		3 mM Ca²⁺/Mg²⁺			3 mM Ca²⁺/Mg²⁺

			+ 1mM EDTA			+1 mM EDTA		+ 1 mM EDTA		+1 mM EDTA
CS-susceptible	0.5	1	0.5	0.5	0.5	1	0.25	0.25	0.5	0.25
E. coli (n = 3)	(0.5–2)	(0.5–2)	(0.5–2)	(0.5–2)	(0.5–4)	(1–2)	(0.25–2)	(0.25–2)	(0.5–2)	(0.25–1)
mcr-1-positive	4	32^a	32^a	24^a	>64^a,b	6^b,c	64^a	4^d	32^a	16
E. coli (n = 3)	(4–8)	(16–64)	(8–64)	(16–32)	(64−>64)	(2–16)	(32−>64)	(2–16)	(4–64)	(2–32)

≥4 fold (± 2 log₂) difference with p < 0.01 ^a – compared to CAMHB pH 7.3. ^b – compared to CAMHB pH 6.1. ^c – compared to CAMHB pH 6.1 + 3 mM Ca²⁺/Mg²⁺. ^d – compared to artificial urine pH 6.1.