Table 2. Various biosensors for detection of A (H1N1) virus.
S.N.o | Sensor type | Gene/protein | Sensitivity/L.O.D | Sample type | Detection time | References |
---|---|---|---|---|---|---|
1 | AuNP immunosensor | HA, NA antibody | 50.5 pg/ml | H1N1 virus | – | [54] |
2 | Fluorescent immunosensor | HA/fusion antibody | Not reported | H1N1 Virus | – | [73] |
3 | Surface plasmon resonance | HA | 4.5 pmol l-1 | H1N1 Virus | – | [74] |
4 | Immunosensor /SPR | HA /antibody | 30 PFU/ml | labelled anti-HA | 20 min | [75] |
5 | Immunosensor | M1/polyclonal antibody | 80–100 virions/µl | H1N1 virus | 30 min | [79] |
6 | PEDOT with galatcose | HA binding | 0.12, 0.013 HAU | H1N1 virus | – | [80] |
7 | BDD | M1 antibody | 1 fg/ml | antibody-M1 | 5 min | [83] |
8 | SiO2-IO | HA antibody | 103–105 PFU | H1N1 virus | – | [84] |
9 | SWCNT immunoassay | anti- HIN1 | 180 TCID50ml | H1N1 Virus | – | [88] |
10 | Impedance aptasensor | DNA aptamer | 0.9 pg/µl | H1N1 virus | – | [89] |
11 | DPM-coated gold electrode | His6-H1 HA | 1 × 109 to 1 × 108 fold | HA antibody in sera | – | [90] |
12 | QCM immunosensor | Anti-MA | 1 × 103 pfu/ml | H1N1 virus | >100 min | [95] |
13 | FET Biosensor | HA binding | 6000 HA mol/20 µl | HA protein | – | [112] |
Notes: HAU, hemagglutinin unit; TCID, tissue culture infective dose; PFU, plaque forming unit; PEDOT, Poly (3,4-ethylenedioxythiophene); DPM, dipyrromethene; BDD, Boron doped diamond; HA, hemagglutinin; MA. Matrix.