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. 2020 Jan 29;14:2. doi: 10.3389/fncom.2020.00002

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Copyright © 2020 Provenzano, Washington and Baraniuk.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Overall pattern depicting the difference in brain activation between CFS and sedentary control groups on Day 1 and Day 2. Axial slices show the pattern of 29 AAL regions that had significantly different numbers of activated voxels (t > 3.17, p < 0.001) in the 2 > 0-black condition based on logistic regression analysis. The complete pattern reflects the overall changes in all regions. Individual AAL regions are color coded for clarity. The colors do not indicate differences in BOLD signal intensity, t-values, logistic regression coefficients or Pearson's correlation coefficients for any single region between the two groups.