Table 2.
Histologic findings regarding allograft inflammation and fibrosis classified based on Banff criteria for acute allograft rejection and liver allograft fibrosis scoring, respectively.
| Factor | No. of patients | % |
|---|---|---|
| Banff criteria for acute rejection | ||
| Normal, RAI = 0 | 34 | 51.5 |
| Indeterminate, RAI = 1–2 | 23 | 34.8 |
| Mild rejection, RAI = 3–4 | 8 | 12.1 |
| Moderate rejection, RAI = 5–7 | 1 | 1.5 |
| Severe rejection, RAI = 8–9 | — | — |
| Portal inflammation score | ||
| 0 | 34 | 51.5 |
| 1 | 24 | 36.4 |
| 2 | 6 | 9.1 |
| 3 | 2 | 3.0 |
| Bile duct damage score | ||
| 0 | 57 | 86.4 |
| 1 | 8 | 12.1 |
| 2 | 1 | 1.5 |
| 3 | — | — |
| Venous endothelial inflammation score | ||
| 0 | 59 | 89.4 |
| 1 | 7 | 10.6 |
| 2 | — | — |
| 3 | — | — |
| LAF score for Fibrosis | ||
| Portal and periportal fibrosis | ||
| 0 | 41 | 62.1 |
| 1 | 18 | 27.3 |
| 2 | 7 | 10.6 |
| 3 | — | — |
| Perisinusoidal | ||
| 0 | 46 | 69.7 |
| 1 | 13 | 19.7 |
| 2 | 7 | 10.6 |
| 3 | — | — |
| Centrilobular | ||
| 0 | 47 | 71.2 |
| 1 | 17 | 25.8 |
| 2 | 2 | 3.0 |
| 3 | — | — |
| Total | ||
| 0 | 25 | 37.9 |
| 1 | 20 | 30.3 |
| 2 | 9 | 13.6 |
| 3 | 6 | 9.1 |
| 4 | 6 | 9.1 |
Rejection activity index RAI, Liver allograft fibrosis LAF.