Table 5.
Multivariable logistic regression analyses on potential risk factors for different scores of LAF scoring system.
| LAF score | Variables | No. | OR | 95% CI | P-value |
|---|---|---|---|---|---|
| Portal 1–2 | AST/ALT above 50 U/L > 5 | 28 | 3.156 | 1.059–9.410 | 0.039 |
| Experience of PTLD | 9 | 7.371 | 1.320–41.170 | 0.023 | |
| Portal 2 | AST/ALT above 100 U/L > 5 | 11 | 13.978 | 2.025–96.460 | 0.007 |
| Experience of rejection | 29 | 4.261 | 0.399–45.448 | 0.230 | |
| Sinusoidal 1–2 | AST/ALT above 100 U/L > 5 | 11 | 4.897 | 1.167–20.548 | 0.030 |
| At the time of protocol biopsy | |||||
| IgG ≥ 1,700 mg/dL | 5 | 3.414 | 0.262–44.461 | 0.349 | |
| GGT ≥ 50 U/L | 15 | 2.832 | 0.711- | 0.140 | |
| Positive for any autoantibody | 25 | 3.298 | 11.278 1.039–10.473 | 0.043 | |
| Sinusoidal 2 | At the time of protocol biopsy | ||||
| GGT ≥ 60 U/L | 14 | 6.201 | 1.096–35.097 | 0.039 | |
| Positive for FANA | 22 | 5.880 | 0.963–35.904 | 0.055 | |
| Centrilobular 1–2 | Donor sex (Female against Male) | 25 | 0.021 | 0.001–0.345 | 0.007 |
| Donor age ≥ 30 years | 50 | 0.049 | 0.005–0.460 | 0.008 | |
| Experience of PTLD | 9 | 8.822 | 1.378–56.455 | 0.022 |
Liver allograft fibrosis LAF, aspartate aminotransferase AST, alanine aminotransferase ALT, post-transplantation lymphoproliferative disease PTLD, gamma-glutamyl transferase GGT, Fluorescent antinuclear antibody FANA.
*Presented variables were significant factors analyzed in the univariable analyses.