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. 2020 Feb 4;10:1840. doi: 10.1038/s41598-020-58760-7

Table 3.

Comparison of cardiovascular risk parameters according to the 25th and 50th percentiles (P25 and P50, respectively) of serum ucOC logarithm by sex-adjusted univariate analysis of variance.

Total sample P25 of ucOC levels P50 of ucOC levels
<2.53 ng/mL (n = 57) ≥2.53 ng/mL (n = 170) p <4.58 ng/mL (n = 114) ≥4.58 ng/mL (n = 113) p
mean SD mean SD mean SD mean SD
BMI 32.73 3.37 32.41 3.61 0.535 32.58 3.23 32.41 3.85 0.701
WC 109.78 9.80 106.88 10.27 0.260 108.77 10.01 106.44 10.31 0.353
mean BP 103.74 12.16 103.17 11.15 0.819 103.25 11.26 103.38 11.56 0.488
HDL cholesterol 45.35 7.79 50.76 10.28 0.002 47.31 9.13 51.52 10.39 0.009
FPG 111.63 34.29 99.05 20.86 0.001 106.11 28.16 98.27 21.76 0.013
TG 192.19 98.63 162.47 63.88 0.008 178.17 82.87 161.63 65.51 0.090
HbA1c 6.33 0.99 5.84 1.08 0.006 6.09 0.94 5.86 1.19 0.126
CV-ZS 1.06 3.38 −0.40 2.41 0.000 0.42 2.95 −0.49 2.47 0.011
Framingham 17.56 8.29 13.19 6.75 0.001 15.66 8.01 12.84 6.41 0.015
REGICOR 7.11 4.01 5.95 2.74 0.055 6.67 3.55 5.80 2.61 0.133
MetS – T2D group P25 of ucOC levels P50 of ucOC levels
<3.00 ng/mL (n = 44) ≥3.00 ng/mL (n = 131) p 4.91 ng/mL (n = 88) ≤4.91 ng/mL (n = 87) p
mean SD mean SD mean SD mean SD
BMI 32.75 3.16 32.37 3.73 0.743 32.57 3.32 32.40 3.82 0.697
WC 109.79 9.81 106.51 10.26 0.277 108.50 9.75 106.49 10.70 0.959
mean BP 104.64 11.53 102.64 11.29 0.421 103.46 11.49 103.12 11.32 0.789
HDL cholesterol 45.92 7.86 51.16 10.49 0.006 47.73 9.24 51.53 10.52 0.038
FPG 109.54 31.18 98.52 21.14 0.509 105.29 27.02 98.29 22.79 0.167
TG 184.22 93.15 162.74 63.14 0.196 176.57 80.90 161.50 66.27 0.162
HbA1c 6.19 0.97 5.86 1.12 0.438 6.04 0.90 5.89 1.26 0.373
CV-ZS 0.96 3.15 −0.53 2.39 0.010 0.31 2.91 −0.47 2.49 0.097
Framingham 16.57 8.15 13.17 6.75 0.726 15.50 7.82 12.71 6.50 0.481
REGICOR 7.03 3.82 5.85 2.67 0.029 6.54 3.44 5.86 2.68 0.353

BMI: body mass index; WC: waist circumference; FPG: fasting plasma glucose; TG: triglyceride; ucOC: undercarboxylated osteocalcin; CV-ZS: cardiovascular risk score. Data for continuous variables are expressed as mean ± standard deviation (SD). Univariate analysis of variance using a general linear factorial model adjusted by sex was used for comparisons between quantitative variables. Significance was set at p < 0.05.