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. 2020 Jan 20;52(1):41–55. doi: 10.1038/s12276-019-0356-6

Fig. 8. Schematic diagram of the USP21/YY1/SNHG16/miR-4500 axis.

Fig. 8

USP21 deubiquitinates and stabilizes YY1, and YY1 transcriptionally activates lncRNA SNHG16, which further upregulates USP21 expression by binding to and suppressing miR-4500.