Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
[A] The interfacial region of the β-subunit of RNAP highlighted in Maroon. [B]. The maximum destabilizing effect a mutation can induce on the interface stability, is predicted by mCSM-PPI and mapped on the structure. Red indicates regions that are highly destabilized by mutations (-5.108 Kcal/mol) while the blue indicates stable regions. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)
