Fig. 2.

RQ treatment decreased M2-like phenotypes. a J774a.1 and Raw264.7 cells were each divided into six groups, M0, M1, M2, M0 + RQ, M1 + RQ, and M2 + RQ. p-STAT1 and iNOS was found to be upregulated in M1 and M1 + RQ groups. p-STAT6 and arginase-1 was downregulated in M2 and M2 + RQ groups. b Real-time PCR showed increased expression of M1-related genes in M0 cell and decreased expression of M2-related genes in M2 cells after RQ treatment compared with M0 baseline control