Table 2.
tPNF (hours) | t2 (hours) | ECC1 (hours) | First cleavage | Secord cleavage | Third cleavage | ||
---|---|---|---|---|---|---|---|
Control 1 | Embryo 1 | 23.6 | 25.8 | 0.25 | Normal, cleaved to 2-cell | Normal, 2-cell cleaved to 4-cell | Normal, 4-cell cleaved to 8-cell |
Embryo 2 | 24.0 | 25.9 | 0.17 | ||||
Embryo 3 | 24.0 | 25.5 | 0.07 | ||||
Embryo 4 | 24.5 | 26.0 | 0.08 | ||||
Embryo 5 | 22.2 | 24.5 | 0.08 | ||||
Control 2 | Embryo 1 | 20.5 | 26.4 | 0.17 | Normal, cleaved to 2-cell | Normal, 2-cell cleaved to 4-cell | Normal, 4-cell cleaved to 8-cell |
Embryo 2 | 24.5 | 27.5 | 0.25 | ||||
Embryo 3 | 25.9 | 27.1 | 0.67 | ||||
Embryo 4 | 24.9 | 29.2 | 0.17 | ||||
Embryo 5 | 21.1 | 28.5 | 0.25 | ||||
Embryo 6 | 20.9 | 27.3 | 0.17 | ||||
Patient 1 | Embryo 1 | 55.6 | 59.7 | 1.42 | DC to 5-cell, FR | DA | |
Embryo 2 | 26.2 | 34.7 | 5.67 | DC to 3-cell, BF | 1/3 DA to 5-cell, FR | DA | |
Embryo 3 | 32.5 | 36.4 | 1.33 | DC to 4-cell, BF | DA | ||
Embryo 4 | 23.1 | / | / | FC | DC to 4-cell | DA | |
Embryo 5 | 27.6 | 31.5 | 1.33 | UB to 2-cell | 1/2 DA to 3-cell | DA | |
Embryo 6 | 23.3 | / | / | FC | DC to 3-cell and RC to 2-cell, FR | DA | |
Embryo 7 | 31.6 | 50.8 | 15.67 | DC to 3-cell and RC to 2-cell, FR | 1/2 DA to 3-cell | 1/3 DA to 5-cell | |
Embryo 8 | 33.8 | 36.6 | 1.75 | DC to 3-cell | DA | ||
Patient 2 | Embryo 1 | 49.0 | 52.1 | 1.67 | DC to 3-cell, BF | DA | |
Embryo 2 | 33.8 | 40.0 | 1.58 | DC to 4-cell and RC to 3-cell, FR | DA | ||
Embryo 3 | 23.2 | 26.2 | 0.17 | DC to 4-cell | DA |
tPNF, timing of the fading of both pronuclei; t2, timing of division to two completely separated blastomeres, for the patients, the t2 indicated the timing of the finish of the first division; ECC1, the duration of the first division; DC, direct cleavage; DA, developmental arrest; FC, failed cytokinesis; RC, reverse cleavage; UB, uneven blastomeres; BF, big fragment; FR, scattered fragments after division