Table 2.
Extracted data regarding the stimulation protocols employed for FPS and LPS respectively
| Studies | Stimulation protocols employed | |||||
|---|---|---|---|---|---|---|
| FPS | First trigger | Pre-existing follicles required for LPS | Initiation of LPS (days following 1st OR) | LPS | Second trigger | |
| Kuang et al. 2014 [6] | CC, Let, HMG | GnRH-ag, Ibup | At least 2 antral follicles 2–8 mm | 0–1 days | Let, HMG, Medrox | GnRH-ag, Ibup |
| Ubaldi et al. 2016 [9] | rFSH, rLH, GnRH-antag | Bus | NA | 5 days | rFSH, rLH, GnRH-antag | Bus |
| Liu et al. 2017 [20] | rFSH, rLH | rHCG | At least one antral follicle 6–11 mm | 1–3 days | HMG | rHCG |
| Zhang et al. 2017 [21] | CC, Gon | GnRH-ag | Antral follicles 5–10 mm | 1 day | Gon | rHCG |
| Rashtian et al. 2017 [7] | Let, CC, Gon, GnRH-antag | GnRH-ag | At least 1 antral follicle < 11 mm | 1 day | Let, CC, Gon | rHCG |
| Jin et al. 2018 [19] | Let or CC, HMG, GnRH-antag | GnRH-ag | NA | 1–3 days | CC, HMG | rHCG |
| Vaiarelli et al. 2018 [10] | E2 valerate, rFSH, rLH, GnRH-antag | Bus | NA | 5 days | rFSH, rLH, GnRH-antag | Bus |
| Zhang et al. 2018 [22] | CC, HMG | rHCG | At least 2 antral follicles 2–8 mm | 2–7 days | CC, HMG | rHCG |
| Madani et al. 2019 [16] | CC, Let, HMG | Bus, Ibup | At least 2 antral follicles 2–8 mm | 1 day | Let, HMG | Bus |
FPS follicular phase stimulation, LPS luteal phase stimulation, OR oocyte retrieval, CC clomiphene citrate, HMG human menopausal gonadotropin, rFSH recombinant FSH, rLH recombinant LH, rHCG recombinant human chorionic gonadotropin, Gon exogenous gonadotropins, GnRH-ag GnRH agonist, GnRH-antag GnRH antagonist, Bus buserelin, Ibup ibuprofen, Let letrozole, Medrox medroxyprogesterone acetate, NA not applicable