NCT00142285.

Trial name or title	Zinc pneumonia outpatient trial in children < 2 years
Methods	It is a randomised, placebo controlled, double‐blind trial to determine whether zinc can be used in combination with standard antibiotics to reduce the duration of illness and the likelihood of treatment failure among children less than two years old who have non‐severe, outpatient pneumonia in an urban slum among children less than 2 years old
Participants	Children up to 23 months with clinical diagnosis of pneumonia. Exclusion will be those with wheezing at presentation, history of chronic lung, heart or other system disease, suspected tuberculosis, active measles, severe malnutrition requiring hospitalisation, signs of systemic illness (sepsis, meningitis), those who have already received zinc/placebo supplements during this study, those known to be pretreated with antibiotics prior to presenting to clinic
Interventions	Oral antibiotics will be given for a standard 5‐day course, while zinc (20 mg) or placebo will be administered once daily for 10 days Patients will be followed up on a daily basis at home to monitor their progress and document compliance
Outcomes	Primary outcome measures: duration of illness, treatment failure Secondary outcome measures: incidence of subsequent illness episodes (pneumonia and any other)
Starting date	November 2004
Contact information	Abdullah Brooks, ICDRR, B Centre for health and population research
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