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. 2020 Feb 4;3:16. doi: 10.1038/s41746-020-0222-x

Table 1.

Searches for drugs associated with Lyme disease sessions.

Drug searches Lymelight-positive cases (%) Lymelight-negative cases (%) Chi-square p-value
#1 Doxycycline* 26.29 0.51 2,663,557 <0.001
#2 Amoxicillin* 5.71 0.97 65,301 <0.001
#3 Penicillin* 2.56 0.53 23,698 <0.001
#4 Metronidazole+ 2.24 0.58 16,373 <0.001
#5 Ceftriaxone* 2.20 0.14 70,896 <0.001
#6 Ivermectin+ 1.94 0.18 41,860 <0.001
#7 Prednisone# 1.93 1.05 6057 <0.001
#8 Cefuroxime* 1.65 0.06 83,976 <0.001
#9 Trimethoprim/sulfamethoxazole+ 1.56 0.58 7705 <0.001
#10 Rifampicin+ 1.51 0.04 116,892 <0.001
#11 Clindamycin+ 1.21 0.41 6571 <0.001
#12 Ciprofloxacin+ 1.16 0.56 4227 <0.001
#13 Hydroxychloroquine# 1.06 0.12 18,039 <0.001
#14 Permethrin+ 1.05 0.15 14,008 <0.001
#15 Clarithromycin* 0.97 0.07 27,183 <0.001
#16 Tinidazole+ 0.95 0.02 87,125 <0.001
#17 Cefalexin+ 0.94 0.41 3828 <0.001
#18 Amoxicillin/clavulanic acid* 0.85 0.27 4917 <0.001
#19 Fluconazole+ 0.85 0.30 4309 <0.001
#20 Hash Oil+ 0.83 0.21 3991 <0.001

Searches for drugs associated with Lyme disease sessions. Percentage figures show the probability of searching for the drug. The “*” symbol denotes recommended treatment for Lyme Disease (per Clinical Practice Guidelines), the “+” symbol denotes non-recommended treatment for Lyme Disease, and the “#” symbol denotes recommended treatment for arthritis.