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. 2020 Jan 20;52(1):92–104. doi: 10.1038/s12276-019-0361-9

Fig. 3. Nonallergic eosinophilic asthma phenotype of the DEP/rIL-23 model.

Fig. 3

a Airway resistance at doses of 50 and 100 mg/mL methacholine (MCh). b Eosinophils, neutrophils, and lymphocytes in bronchoalveolar lavage fluid. c CD11b+siglecF+CD11c− cells in bronchoalveolar lavage fluid. d IL-13 or IL5-producing type 2 innate lymphoid cells (CD45+Lin− ICOS+) in lung homogenate. e IL-17A-producing type 3 innate lymphoid cells (CD45+Lin− CD25+) in lung homogenate. f, g IL-13-producing or IL-17A-producing CD4+ T cells in lung homogenate. h IL-33, TSLP, and IL-1β levels in lung homogenate. *P < 0.05, **P < 0.01 between two groups; #P < 0.05 compared to the control group; DEP diesel exhaust particle; ns, not significant; PBS phosphate-buffered saline.