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. 2020 Jan 20;52(1):66–78. doi: 10.1038/s12276-019-0358-4

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Protein abundance of ITGA6 was significantly reduced in LA+ TE+ patients compared to healthy controls (p = 0.01) and patients without thrombosis (p = 0.002). Each dot represents a measurement of a single patient. The patient with CAPS is visualized as a red rhombus. The line between the dots represents the mean. FDR-corrected t-test was used to compare differences between groups. LA lupus anticoagulant, TE thromboembolism, 2D-DIGE two-dimensional differential in-gel electrophoresis, CAPS catastrophic antiphospholipid antibody syndrome.