. 2020 Jan 20;52(1):66–78. doi: 10.1038/s12276-019-0358-4

Table 3.

Spearman correlation coefficients of altered platelet proteins and plasma levels of H3Cit and P4HB with aPLAs.

Protein name	Gene name	beta2IgG		beta2IgM		ACAIgG		ACAIgM		aPTT-LA
Protein name	Gene name	rho	p-value	rho	p-value	rho	p-value	rho	p-value	rho	p-value
60 kDa heat shock protein	HSPD1	0.17	0.10189	0.15	0.14360	0.17	0.09754	0.15	0.14584	0.04	0.68816
78 kDa glucose-regulated protein	HSPA5	0.32	0.00197	0.17	0.10405	0.25	0.01634	0.26	0.01254	0.13	0.20740
Actin	ACTB	0.19	0.08615	0.00	0.99256	0.24	0.02999	0.05	0.62676	0.237	0.03334
Albumin	ALB	−0.11	0.30463	0.18	0.08227	−0.03	0.78719	0.13	0.21880	0.00	0.97263
Apolipoprotein A1	APOA1	−0.26	0.01510	−0.07	0.54604	−0.32	0.00291	−0.14	0.19751	−0.25	0.02460
ATP synthase subunit beta	ATB5B	0.10	0.34481	0.10	0.34685	0.07	0.50187	0.10	0.33366	−0.03	0.75926
Bridging integrator 2	BIN2	−0.09	0.41266	−0.23	0.02367	−0.13	0.22210	−0.23	0.02925	−0.28	0.00674
Calreticulin	CALR	0.39	0.00013	0.22	0.03227	0.33	0.00122	0.27	0.01003	0.22	0.03549
Chloride intracellular channel protein 1	CLIC1	−0.16	0.13441	0.02	0.83857	−0.05	0.64154	−0.03	0.79319	−0.01	0.91898
Fermitin family homolog 3	FERMT3	−0.19	0.06772	−0.12	0.26248	−0.21	0.04817	−0.14	0.19047	−0.33	0.00155
Fibrinogen beta chain	FGB	0.24	0.02130	0.17	0.10211	0.27	0.01106	0.22	0.04155	0.35	0.00103
		0.16	0.15117	0.12	0.25037	0.12	0.25475	0.14	0.20021	0.16	0.13852
		0.14	0.19122	0.05	0.61319	0.14	0.16865	0.07	0.53253	0.17	0.09965
		0.29	0.00653	0.24	0.02868	0.24	0.02427	0.25	0.02115	0.09	0.43085
Heat shock protein HSP 90-alpha	HSP90AA1	0.29	0.00520	0.20	0.05763	0.38	0.00018	0.26	0.01184	0.28	0.00707
Integrin alpha-6	ITGA6	−0.21	0.04766	−0.09	0.37817	−0.14	0.19038	−0.15	0.15803	−0.08	0.47165
Leukocyte elastase inhibitor	SERPINB1	−0.20	0.05664	−0.04	0.71912	−0.16	0.11436	−0.07	0.47704	−0.16	0.13450
Microtubule-associated protein RP/EB family member 2	MAPRE2	0.15	0.16008	0.22	0.04858	0.12	0.26731	0.19	0.08717	0.24	0.02602
Myosin 9	MYH9	−0.14	0.16585	−0.10	0.33328	−0.11	0.27362	−0.17	0.09670	−0.01	0.93748
Nucleosome assembly protein 1-like 1	NAP1L1	0.06	0.59095	0.04	0.70443	0.01	0.95578	0.06	0.58759	−0.01	0.90886
Proteasome activator complex subunit 1	PSME1	0.26	0.01136	0.24	0.01895	0.23	0.02776	0.24	0.01957	0.27	0.00963
Protein disulfide isomerase A1	P4HB	0.32	0.00201	0.22	0.03279	0.24	0.02017	0.26	0.01355	0.17	0.11490
Protein disulfide isomerase A6	PDIA6	0.26	0.01082	0.15	0.16264	0.23	0.02398	0.19	0.06515	0.16	0.12280
Ras-related protein Rab-27B	RAB27B	−0.10	0.36735	−0.11	0.29290	−0.12	0.24516	−0.12	0.25889	−0.27	0.00951
Translationally controlled tumor protein	TPT1	0.13	0.21697	0.12	0.24945	0.13	0.22414	0.15	0.14543	0.07	0.50463
Tropomyosin alpha-3 chain	TPM3	0.02	0.89045	−0.09	0.42401	−0.04	0.73541	−0.09	0.42459	−0.23	0.03298
Vinculin	VCL	0.31	0.00635	0.17	0.14116	0.27	0.01620	0.26	0.02380	0.20	0.08571
		0.32	0.00191	0.20	0.05917	0.32	0.00234	0.27	0.00868	0.29	0.00667
		0.28	0.01027	0.18	0.10479	0.27	0.01329	0.25	0.02180	0.31	0.00420
		−0.17	0.10760	−0.25	0.01770	−0.19	0.07469	−0.25	0.01675	−0.33	0.00145
H3Cit ELISA [ng/ml]		0.21	0.04758	0.18	0.07782	0.18	0.08715	0.22	0.03193	0.29	0.00506
P4HB ELISA [ng/ml]		0.41	0.00004	0.32	0.00164	0.41	0.00005	0.35	0.00064	0.38	0.00024

Statistically significant correlations are highlighted in bold

aPLAs antiphospholipid autoantibodies