Table 4.
Univariate analyses on DFI across different staging systems proposed by Eighth edition AJCC 2018 and using Ki67-integrated PS.
| System classification | HR | CI | p value | |
|---|---|---|---|---|
|
AJCC 2018 anatomic stage (AS) Harrell c test 0.6993; AIC 672.6299 |
I | 1 | ||
| II | 4.54 | 2.63–7.82 | <0.001 | |
| III | 4.62 | 1.58–13.48 | 0.005 | |
|
AJCC 2018 Prognostic stage (PS) Harrell c test 0.6993; AIC 672.6299 |
I | 1 | ||
| II | 3.44 | 1.80–6.57 | <0.001 | |
| III | 3.87 | 1.73–8.66 | 0.005 | |
|
AJCC 2018 PS integrated by Ki67 (Ki67-PS) Harrell c test 0.6094; AIC 674.1635 |
I | 1 | ||
| II | 3.27 | 1.67–6.36 | 0.001 | |
| III | 3.79 | 1.70–8.47 | 0.001 | |
|
AJCC 2018 PS and Ki67-PS Harrell c test 0.6265 |
IA | 1 | ||
| IB > IA | 1.66 | 0.62–4.44 | 0.307 | |
| IB | 2.79 | 1.41–5.53 | 0.003 |