Table 3.

Multivariate analysis of OS and RFS in the training, validation, and combined sets.

Covariates	OS				RFS
	HR	p	q	95% CI	HR	p	q	95% CI
Training set
Group 1 vs Group 2	5.36	<0.0001	<0.0001	2.93–9.80	2.33	0.010	0.022	1.23–4.41
Stage I and II vs III and IV	2.78	0.153	0.172	0.68–11.33	1.67	0.264	0.396	0.68–4.11
Age ≤55 vs >55 years	1.78	0.009	0.016	1.16–2.74	0.90	0.592	0.592	0.62–1.32
Validation set
Group 1 vs Group 2	3.88	0.001	0.003	1.71–8.82	1.85	0.164	0.295	0.78–4.38
Stage I and II vs III and IV	2.08	0.069	0.089	0.95–4.57	9.98	0.001	0.005	2.42–41.22
Age ≤55 vs >55 years	1.26	0.369	0.369	0.76–2.10	0.85	0.557	0.592	0.50–1.46
Combined set
Group 1 vs Group 2	4.76	<0.0001	<0.0001	2.95–7.67	2.25	0.002	0.006	1.35–3.73
Stage I and II vs III and IV	2.26	0.025	0.038	1.11–4.60	3.96	<0.0001	<0.0001	1.86–8.46
Age ≤55 vs >55 years	1.59	0.005	0.011	1.15–2.20	0.90	0.497	0.592	0.67–1.22

Bold indicates statistically significant p values