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. 2020 Feb 4;10:1807. doi: 10.1038/s41598-020-58368-x

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Detachment of PVAT from absolute length of ring abolishes its assistance of arterial stretch relaxation. (a) Image of aortic rings from the same animal +PVAT, +/−PVAT (intact only on ends), and −PVAT. Numbers beneath each vessel image is the vessel mass presented as means ± SEM for the N = 5 vessels experimented on to generate data in this figure. Quantitation of cumulative stress relaxation (b) and active contraction to PE (c) reporting absolute values (left) and area under the curve (right). Points/bars represent means ± SEM for the number of animals in parentheses. *Significant differences (p value reported in figure) as determined by a one-way ANOVA with Tukey’s post hoc determinations comparing averages as indicated by the tied bar.