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. 2020 Feb 4;10:1783. doi: 10.1038/s41598-020-58687-z

Table 2.

Group comparisons of the baseline cervical spinal cord cross-sectional area.

Group N CSA in mm2 Statistics
ALS 158 61 [7] F(1,240) = 10.7, p = 0.001
Controls 86 64 [7]
Limb-onset ALS 110 60 [7] F(1,153) = 5.4, p = 0.02
Bulbar-onset ALS 45 62 [6]
Classic ALS 108 61 [7] F(3,154) < 1.7, p > 0.2
LMND ALS 27 59 [6]
UMND ALS 14 62 [7]
PLS 9 56 [7]
Sporadic ALS 49 61 [7] F(1,61) = 1, p = 0.4
Familial ALS 14 63 [8]
No NIV 122 61 [7] F(1,136) = 0.9, p = 0.4
NIV 16 61 [6]

Mean [SD] of the baseline cervical spinal cord cross-sectional area (CSA) is given. ALS, amyotrophic lateral sclerosis; LMND, lower motor neuron dominant; N, number; NIV, non-invasive ventilation; PLS, primary lateral sclerosis; UMND, upper motor neuron dominant. P-values ≤ 0.05 were deemed statistically significant. Statistical models are adjusted for baseline age.