Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Feb 4;10:1821. doi: 10.1038/s41598-020-58864-0

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

ROR1 regulates ABCB1 protein and mRNA expression. (A) Immunoblot assessing ROR1 and ABCB1 protein expression after ROR1 knockdown via siRNA (top panel) or ROR1 inhibition with StrC (bottom panel) in MDA-MB-231. Full length blots are presented in the Supplementary Fig. S9. (B) Immunofluorescence labelling ABCB1 in SUM-159PT/R cells transfected with either siROR1 or scRNA (C,D) qPCR investigating ROR1 and ABCB1 mRNA levels in MDA-MB-231 following ROR1 knockdown via siRNA (B) or inhibition with StrC (C). Statistical analyses via student’s t test. N = 3. ****p < 0.0001.