Table 1.
Data of the 4 groups of enrolled patients and healthy volunteers
| Secondary IgA nephropathy | IgA nephropathy | Nephropathy control | Healthy control | |
|---|---|---|---|---|
| No. of participants | 100 | 32 | 41 | 39 |
| Age (yr) | 45.67 ± 14.56 | 37.88 ± 11.16 | 39.8 ± 17.56 | 34.95 ± 8.69 |
| Sex (male/female) | 59/41 | 19/13 | 18/23 | 17/22 |
| Proteinuria (g/d) | 2.65 | 2.97 | 5.26 | |
| SBP (mm Hg) | 131 ± 18 | 131 ± 11 | 132 ± 17 | |
| DBP (mm Hg) | 81 ± 13 | 83 ± 9 | 84 ± 14 | |
| MAP (mm Hg) | 98 ± 14 | 99 ± 9 | 100 ± 14 | |
| SCr (mmol/l) | 158 ± 150 | 240 ± 227 | 191 ± 229 | |
| eGFR (ml/min per 1.73 m2) | 64.9 ± 35 | 49.3 ± 33.8 | 71 ± 43 | |
| Serum IgA (g/l) | 4.27 ± 1.60 | 3.30 ± 1.14 | 1.92 ± 0.89 | |
| Serum IgG (g/l) | 11.92 ± 5.21 | 9.96 ± 2.61 | 9.77 ± 6.45 | |
| Serum C3 (g/l) | 0.98 ± 0.27 | 0.87 ± 0.18 | 0.83 ± 0.47 | |
| Serum C4 (g/l) | 0.28 ± 0.35 | 0.21 ± 0.05 | 0.19 ± 0.13 |
DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; MAP, mean arterial pressure; SBP, systolic blood pressure; SCr, serum creatinine.