Table 3.
Subgroup analyses of crude and adjusted hazard ratios (95% confidence interval) of depression for peptic ulcer according to age and sex.
| Characteristics | Hazard ratios for Peptic ulcer | |||
|---|---|---|---|---|
| Crude† | P-value | Adjusted†‡ | P-value | |
| Age <40 years old, men (n = 18,245) | ||||
| Depression | 1.30 (1.13–1.49) | <0.001* | 1.17 (1.02–1.35) | 0.029* |
| Control I | 1.00 | 1.00 | ||
| Age <40 years old, women (n = 33,100) | ||||
| Depression | 1.36 (1.22–1.51) | <0.001* | 1.25 (1.12–1.39) | <0.001* |
| Control I | 1.00 | 1.00 | ||
| Age 40–59 years old, men (n = 20,185) | ||||
| Depression | 1.25 (1.12–1.39) | <0.001* | 1.15 (1.03–1.28) | 0.015* |
| Control I | 1.00 | 1.00 | ||
| Age 40–59 years old, women (n = 37,775) | ||||
| Depression | 1.26 (1.17–1.36) | <0.001* | 1.15 (1.06–1.24) | <0.001* |
| Control I | 1.00 | 1.00 | ||
| Age ≥60 years old, men (n = 13,750) | ||||
| Depression | 1.01 (0.87–1.17) | 0.926 | 0.90 (0.78–1.05) | 0.167 |
| Control I | 1.00 | 1.00 | ||
| Age ≥60 years old, women (n = 28,475) | ||||
| Depression | 1.23 (1.11–1.36) | <0.001* | 1.11 (1.00–1.23) | 0.053 |
| Control I | 1.00 | 1.00 | ||
*Cox-proportional hazard regression model, Significance at P < 0.05
†Stratified model for age, sex, income, and region of residence.
‡Adjusted model for Charlson Comorbidity index calculated without peptic ulcer.